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Knots can impair protein degradation by ATP-dependent proteases
ATP-dependent proteases translocate proteins through a narrow pore for their controlled destruction. However, how a protein substrate containing a knotted topology affects this process remains unknown. Here, we characterized the effects of the trefoil-knotted protein MJ0366 from Methanocaldococcus j...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5604015/ https://ncbi.nlm.nih.gov/pubmed/28847957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705916114 |
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