Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease

Neurological diseases caused by encephalitic flaviviruses are severe and associated with high levels of mortality. However, little is known about the detailed mechanisms of viral replication and pathogenicity in the brain. Previously, we reported that the genomic RNA of tick-borne encephalitis virus...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hirano, Minato, Muto, Memi, Sakai, Mizuki, Kondo, Hirofumi, Kobayashi, Shintaro, Kariwa, Hiroaki, Yoshii, Kentaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604007/
https://ncbi.nlm.nih.gov/pubmed/28847946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704454114
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