West Nile virus capsid protein inhibits autophagy by AMP-activated protein kinase degradation in neurological disease development

West Nile virus (WNV) belongs to the Flaviviridae family and has emerged as a significant cause of viral encephalitis in birds and animals including humans. WNV replication directly induces neuronal injury, followed by neuronal cell death. We previously showed that accumulation of ubiquitinated prot...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kobayashi, Shintaro, Yoshii, Kentaro, Phongphaew, Wallaya, Muto, Memi, Hirano, Minato, Orba, Yasuko, Sawa, Hirofumi, Kariwa, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977728/
https://ncbi.nlm.nih.gov/pubmed/31971978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008238
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