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Physicochemical, Stress Degradation Evaluation and Pharmacokinetic Study of AZGH102, a New Synthesized COX2 Inhibitors after I.V. and Oral Administration in Male and Female Rats.

Coxibs such as celecoxib, rofecoxib, and valdecoxib are introduced as selective COX-2 inhibitors to the market. It has been reported that inhibition of COX-2 beside traditional effects of NSAIDs, reduces the risk of colorectal, breast and lung cancers and also slow the progress of Alzheimer’s diseas...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Bahmanof, Hoda, Dadashzadeh, Simin, Zarghi, Afshin, Shafaati, Alireza, Foroutan, Seyed Mohsen
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603853/
https://ncbi.nlm.nih.gov/pubmed/28979299
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