Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase

The RNA-degrading exosome mediates the processing and decay of many cellular transcripts. In the yeast nucleus, the ubiquitous 10-subunit exosome core complex (Exo-9–Rrp44) functions with four conserved cofactors (Rrp6, Rrp47, Mtr4, and Mpp6). Biochemical and structural studies to date have shed ins...

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Vydáno v:Cell Rep
Hlavní autoři: Falk, Sebastian, Bonneau, Fabien, Ebert, Judith, Kögel, Alexander, Conti, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603729/
https://ncbi.nlm.nih.gov/pubmed/28877463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.033
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