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Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance

Mtr4 is a conserved RNA helicase that functions together with the nuclear exosome. It participates in the processing of structured RNAs, including the maturation of 5.8S ribosomal RNA (rRNA). It also interacts with the polyadenylating Trf4-Air2 heterodimer to form the so-called TRAMP (Trf4-Air2-Mtr4...

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Autors principals: Weir, John R., Bonneau, Fabien, Hentschel, Jendrik, Conti, Elena
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901443/
https://ncbi.nlm.nih.gov/pubmed/20566885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004953107
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