The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

The nuclear exosome and its essential co-factor, the RNA helicase MTR4, play crucial roles in several RNA degradation pathways. Besides unwinding RNA substrates for exosome-mediated degradation, MTR4 associates with RNA-binding proteins that function as adaptors in different RNA processing and decay...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Lingaraju, Mahesh, Johnsen, Dennis, Schlundt, Andreas, Langer, Lukas M., Basquin, Jérôme, Sattler, Michael, Heick Jensen, Torben, Falk, Sebastian, Conti, Elena
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662825/
https://ncbi.nlm.nih.gov/pubmed/31358741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11339-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items