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Bicyclic Peptides as Next-Generation Therapeutics

Bicyclic peptides have greater conformational rigidity and metabolic stability than linear and monocyclic peptides and are capable of binding to challenging drug targets with antibody-like affinity and specificity. Powerful combinatorial library technologies have recently been developed to rapidly s...

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Publicat a:Chemistry
Autors principals: Rhodes, Curran A., Pei, Dehua
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603421/
https://ncbi.nlm.nih.gov/pubmed/28590540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201702117
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