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Bicyclic Peptides as Next-Generation Therapeutics
Bicyclic peptides have greater conformational rigidity and metabolic stability than linear and monocyclic peptides and are capable of binding to challenging drug targets with antibody-like affinity and specificity. Powerful combinatorial library technologies have recently been developed to rapidly s...
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| Veröffentlicht in: | Chemistry |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5603421/ https://ncbi.nlm.nih.gov/pubmed/28590540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201702117 |
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