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Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase

Selective autophagy eliminates protein aggregates, damaged organelles, and other targets that otherwise accumulate and cause disease. Autophagy receptors mediate selectivity by connecting targets to the autophagosome membrane. It has remained unknown whether receptors perform additional functions. H...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Kamber, Roarke A., Shoemaker, Christopher J., Denic, Vladimir
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602610/
https://ncbi.nlm.nih.gov/pubmed/26166702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.009
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