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Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase

Selective autophagy eliminates protein aggregates, damaged organelles, and other targets that otherwise accumulate and cause disease. Autophagy receptors mediate selectivity by connecting targets to the autophagosome membrane. It has remained unknown whether receptors perform additional functions. H...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Kamber, Roarke A., Shoemaker, Christopher J., Denic, Vladimir
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602610/
https://ncbi.nlm.nih.gov/pubmed/26166702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.009
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