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Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase

Selective autophagy eliminates protein aggregates, damaged organelles, and other targets that otherwise accumulate and cause disease. Autophagy receptors mediate selectivity by connecting targets to the autophagosome membrane. It has remained unknown whether receptors perform additional functions. H...

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書目詳細資料
發表在:Mol Cell
Main Authors: Kamber, Roarke A., Shoemaker, Christopher J., Denic, Vladimir
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602610/
https://ncbi.nlm.nih.gov/pubmed/26166702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.009
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