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Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase

Selective autophagy eliminates protein aggregates, damaged organelles, and other targets that otherwise accumulate and cause disease. Autophagy receptors mediate selectivity by connecting targets to the autophagosome membrane. It has remained unknown whether receptors perform additional functions. H...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Kamber, Roarke A., Shoemaker, Christopher J., Denic, Vladimir
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602610/
https://ncbi.nlm.nih.gov/pubmed/26166702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.009
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