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Design of Multivalent Inhibitors for Preventing Cellular Uptake

Cellular entry, the first crucial step of viral infection, can be inhibited by molecules adsorbed on the virus surface. However, apart from using stronger affinity, little is known about the properties of such inhibitors that could increase their effectiveness. Our simulations showed that multivalen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Schubertová, Veronika, Martinez-Veracoechea, Francisco J., Vácha, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601900/
https://ncbi.nlm.nih.gov/pubmed/28916832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11735-7
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