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Design of Multivalent Inhibitors for Preventing Cellular Uptake

Cellular entry, the first crucial step of viral infection, can be inhibited by molecules adsorbed on the virus surface. However, apart from using stronger affinity, little is known about the properties of such inhibitors that could increase their effectiveness. Our simulations showed that multivalen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schubertová, Veronika, Martinez-Veracoechea, Francisco J., Vácha, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601900/
https://ncbi.nlm.nih.gov/pubmed/28916832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11735-7
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