BMPR2 promotes invasion and metastasis via the RhoA-ROCK-LIMK2 pathway in human osteosarcoma cells

Bone morphogenetic protein receptor 2 (BMPR2) has been identified in several types of cancer. However, its role in osteosarcoma is largely unknown. We systematically investigated the role of BMPR2 in osteosarcoma cell lines, human tissue samples and xenograft models. The relationship between BMPR2 e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Wang, Shidong, Ren, Tingting, Jiao, Guangjun, Huang, Yi, Bao, Xing, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Sun, Kunkun, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601680/
https://ncbi.nlm.nih.gov/pubmed/28938584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17382
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