BMPR2 promotes invasion and metastasis via the RhoA-ROCK-LIMK2 pathway in human osteosarcoma cells

Bone morphogenetic protein receptor 2 (BMPR2) has been identified in several types of cancer. However, its role in osteosarcoma is largely unknown. We systematically investigated the role of BMPR2 in osteosarcoma cell lines, human tissue samples and xenograft models. The relationship between BMPR2 e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Wang, Shidong, Ren, Tingting, Jiao, Guangjun, Huang, Yi, Bao, Xing, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Sun, Kunkun, Guo, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601680/
https://ncbi.nlm.nih.gov/pubmed/28938584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17382
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