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Prolonged Particulate Hexavalent Chromium Exposure Suppresses Homologous Recombination Repair in Human Lung Cells

Genomic instability is one of the primary models of carcinogenesis and a feature of almost all cancers. Homologous recombination (HR) repair protects against genomic instability by maintaining high genomic fidelity during the repair of DNA double strand breaks. The defining step of HR repair is the...

詳細記述

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書誌詳細
出版年:Toxicol Sci
主要な著者: Browning, Cynthia L., Qin, Qin, Kelly, Deborah F., Prakash, Rohit, Vanoli, Fabio, Jasin, Maria, Wise, John Pierce
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601504/
https://ncbi.nlm.nih.gov/pubmed/27449664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw103
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