Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavalent Chromium Exposure Suppresses the Rad51 Response in Human Lung Cells

The aim of this study was to focus on hexavalent chromium, [Cr(VI)], a chemical carcinogen and major public health concern, and consider its ability to impact DNA double strand break repair. We further focused on particulate Cr(VI), because it is the more potent carcinogenic form of Cr(VI). DNA doub...

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Detaylı Bibliyografya
Yayımlandı:Toxicol Sci
Asıl Yazarlar: Qin, Qin, Xie, Hong, Wise, Sandra S., Browning, Cynthia L., Thompson, Kelsey N., Holmes, Amie L., Wise, John Pierce
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271064/
https://ncbi.nlm.nih.gov/pubmed/25173789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu175
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