Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

O-glycosylation of the Plasmodium sporozoite surface proteins CSP and TRAP was recently identified, but the role of this modification in the parasite life cycle and its relevance to vaccine design remain unclear. Here, we identify the Plasmodium protein O-fucosyltransferase (POFUT2) responsible for...

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書誌詳細
出版年:Nat Commun
主要な著者: Lopaticki, Sash, Yang, Annie S. P., John, Alan, Scott, Nichollas E., Lingford, James P., O’Neill, Matthew T., Erickson, Sara M., McKenzie, Nicole C., Jennison, Charlie, Whitehead, Lachlan W., Douglas, Donna N., Kneteman, Norman M., Goddard-Borger, Ethan D., Boddey, Justin A.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601480/
https://ncbi.nlm.nih.gov/pubmed/28916755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00571-y
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