Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses

Interactions between DNA and proteins are mainly studied through chemical procedures involving bi-functional reagents, mostly formaldehyde. Chromatin immunoprecipitation is used to identify the binding between transcription factors (TFs) and chromatin, and to evaluate the occurrence and impact of hi...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nebbioso, Angela, Benedetti, Rosaria, Conte, Mariarosaria, Carafa, Vincenzo, De Bellis, Floriana, Shaik, Jani, Matarese, Filomena, Della Ventura, Bartolomeo, Gesuele, Felice, Velotta, Raffaele, Martens, Joost H. A., Stunnenberg, Hendrik G., Altucci, Carlo, Altucci, Lucia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601431/
https://ncbi.nlm.nih.gov/pubmed/28916762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12010-5
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