Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival

OBJECTIVES: To determine the relationship between mismatch repair (MMR) classification and clinicopathologic features including tumor volume, and explore outcomes by MMR class in a contemporary cohort. METHODS: Single institution cohort evaluating MMR classification for endometrial cancers (EC). MMR...

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Bibliografski detalji
Izdano u:Gynecol Oncol
Glavni autori: Cosgrove, Casey M, Cohn, David E, Hampel, Heather, Frankel, Wendy L, Jones, Dan, McElroy, Joseph P, Suarez, Adrian A, Zhao, Weiqiang, Chen, Wei, Salani, Ritu, Copeland, Larry J, O’Malley, David M, Fowler, Jeffrey M, Yilmaz, Ahmet, Chassen, Alexis S, Pearlman, Rachel, Goodfellow, Paul J, Backes, Floor J
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601318/
https://ncbi.nlm.nih.gov/pubmed/28709704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2017.07.003
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