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On BH3 Mimetics and Ca(2+) Signaling
[Table: see text] BH3 mimetics are anticancer agents that reproduce the spatial arrangement of the BH3 domain of Bcl‐2 family proteins. Just like the BH3‐only proteins, these compounds bind to the hydrophobic cleft of the pro‐survival Bcl‐2 members such as Bcl‐2 or Bcl‐xL, and disrupt their heterodi...
Sparad:
| I publikationen: | Drug Dev Res |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
John Wiley and Sons Inc.
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601233/ https://ncbi.nlm.nih.gov/pubmed/28804913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.21405 |
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