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Genetic Epistasis Regulates Amyloid Deposition in Resilient Aging
INTRODUCTION: The brain-derived neurotrophic factor (BDNF) interacts with important genetic Alzheimer’s disease (AD) risk factors. Specifically, variants within the SORL1 gene determine BDNF’s ability to reduce Aβ in vitro. We sought to test whether functional BDNF variation interacts with SORL1 gen...
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| Publicado no: | Alzheimers Dement |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601013/ https://ncbi.nlm.nih.gov/pubmed/28322202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.01.027 |
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