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Design, synthesis and experimental validation of novel potential chemopreventive agents using random forest and support vector machine binary classifiers

Compared to the current knowledge on cancer chemotherapeutic agents, only limited information is available on the ability of organic compounds, such as drugs and/or natural products, to prevent or delay the onset of cancer. In order to evaluate chemical chemopreventive potentials and design novel ch...

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Dettagli Bibliografici
Pubblicato in:J Comput Aided Mol Des
Autori principali: Sprague, Brienne, Shi, Qian, Kim, Marlene T., Zhang, Liying, Sedykh, Alexander, Ichiishi, Eiichiro, Tokuda, Harukuni, Lee, Kuo-Hsiung, Zhu, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600879/
https://ncbi.nlm.nih.gov/pubmed/24840854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9748-9
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