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Total synthesis of plagiochin G and derivatives as potential cancer chemopreventive agents
A new and efficient total synthesis has been developed to obtain plagiochin G (22), a macrocyclic bisbibenzyl, and four derivatives. The key 16-membered ring containing biphenyl ether and biaryl units was closed via an intramolecular S(N)Ar reaction. All synthesized macrocyclic bisbibenzyls inhibite...
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| Udgivet i: | Tetrahedron Lett |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283946/ https://ncbi.nlm.nih.gov/pubmed/25574060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.10.038 |
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