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Design, synthesis and experimental validation of novel potential chemopreventive agents using random forest and support vector machine binary classifiers

Compared to the current knowledge on cancer chemotherapeutic agents, only limited information is available on the ability of organic compounds, such as drugs and/or natural products, to prevent or delay the onset of cancer. In order to evaluate chemical chemopreventive potentials and design novel ch...

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Vydáno v:J Comput Aided Mol Des
Hlavní autoři: Sprague, Brienne, Shi, Qian, Kim, Marlene T., Zhang, Liying, Sedykh, Alexander, Ichiishi, Eiichiro, Tokuda, Harukuni, Lee, Kuo-Hsiung, Zhu, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600879/
https://ncbi.nlm.nih.gov/pubmed/24840854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9748-9
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