Androgen Receptor Variants Mediate DNA Repair Following Radiation in Prostate Cancer

Recently, the combination of androgen deprivation therapy (ADT) and radiation therapy (RT) has been shown to block the androgen receptor (AR)-driven DNA damage response (DDR) and enhance RT-mediated cell kill of prostate cancer (PCa). Since ADT may induce expression of AR splice variants (ARVs) we h...

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Publicado no:Cancer Res
Main Authors: Yin, Yi, Li, Rui, Xu, Kangling, Ding, Sentai, Li, Jeffrey, Baek, GuemHee, Ramanand, Susmita G., Ding, Sam, Liu, Zhao, Gao, Yunpeng, Kanchwala, Mohammed, Li, Xiangyi, Hutchinson, Ryan, Liu, Xihui, Woldu, Solomon, Xing, Chao, Desai, Neil B., Feng, Felix Y., Burma, Sandeep, de Bono, Johann, Dehm, Scott M., Mani, Ram S., Chen, Benjamin P.C., Raj, Ganesh V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600864/
https://ncbi.nlm.nih.gov/pubmed/28754673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0164
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