The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer

Transcriptional dysregulation is a hallmark of prostate cancer (PCa). We mapped the RNA polymerase II–associated (RNA Pol II–associated) chromatin interactions in normal prostate cells and PCa cells. We discovered thousands of enhancer-promoter, enhancer-enhancer, as well as promoter-promoter chroma...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Ramanand, Susmita G., Chen, Yong, Yuan, Jiapei, Daescu, Kelly, Lambros, Maryou B.K., Houlahan, Kathleen E., Carreira, Suzanne, Yuan, Wei, Baek, GuemHee, Sharp, Adam, Paschalis, Alec, Kanchwala, Mohammed, Gao, Yunpeng, Aslam, Adam, Safdar, Nida, Zhan, Xiaowei, Raj, Ganesh V., Xing, Chao, Boutros, Paul C., de Bono, Johann, Zhang, Michael Q., Mani, Ram S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410051/
https://ncbi.nlm.nih.gov/pubmed/32343676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134260
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