The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer

Transcriptional dysregulation is a hallmark of prostate cancer (PCa). We mapped the RNA polymerase II–associated (RNA Pol II–associated) chromatin interactions in normal prostate cells and PCa cells. We discovered thousands of enhancer-promoter, enhancer-enhancer, as well as promoter-promoter chroma...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ramanand, Susmita G., Chen, Yong, Yuan, Jiapei, Daescu, Kelly, Lambros, Maryou B.K., Houlahan, Kathleen E., Carreira, Suzanne, Yuan, Wei, Baek, GuemHee, Sharp, Adam, Paschalis, Alec, Kanchwala, Mohammed, Gao, Yunpeng, Aslam, Adam, Safdar, Nida, Zhan, Xiaowei, Raj, Ganesh V., Xing, Chao, Boutros, Paul C., de Bono, Johann, Zhang, Michael Q., Mani, Ram S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410051/
https://ncbi.nlm.nih.gov/pubmed/32343676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134260
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