The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer

Transcriptional dysregulation is a hallmark of prostate cancer (PCa). We mapped the RNA polymerase II–associated (RNA Pol II–associated) chromatin interactions in normal prostate cells and PCa cells. We discovered thousands of enhancer-promoter, enhancer-enhancer, as well as promoter-promoter chroma...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Ramanand, Susmita G., Chen, Yong, Yuan, Jiapei, Daescu, Kelly, Lambros, Maryou B.K., Houlahan, Kathleen E., Carreira, Suzanne, Yuan, Wei, Baek, GuemHee, Sharp, Adam, Paschalis, Alec, Kanchwala, Mohammed, Gao, Yunpeng, Aslam, Adam, Safdar, Nida, Zhan, Xiaowei, Raj, Ganesh V., Xing, Chao, Boutros, Paul C., de Bono, Johann, Zhang, Michael Q., Mani, Ram S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410051/
https://ncbi.nlm.nih.gov/pubmed/32343676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134260
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