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Polymorphisms and mutations in the melanocortin-3 receptor and their relation to human obesity
Inactivating mutations in the melanocortin 3 receptor (Mc3r) have been described as causing obesity in mice, but the physiologic effects of MC3R mutations in humans have been less clear. Here we review the MC3R polymorphisms and mutations identified in humans, and the in vitro, murine, and human coh...
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| Publicado en: | Biochim Biophys Acta |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600657/ https://ncbi.nlm.nih.gov/pubmed/28363697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.03.018 |
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