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Associations of the Melanocortin 3 Receptor C17A + G241A haplotype with body composition and inflammation in African American adults

BACKGROUND: The MC3R haplotype C17A+G241A, which encodes a partially-inactivated receptor, has high prevalence in Individuals of predominately African ancestry. In pediatric cohorts, homozygosity for this common variant has been associated with obesity, reduced lean mass, and greater fasting insulin...

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Detalhes bibliográficos
Publicado no:Ann Hum Genet
Main Authors: DEMIDOWICH, ANDREW P., PARIKH, VIRAJ J., DEDHIA, NICKET, BRANHAM, RACHEL E., MADI, SAMAR A., MARWITZ, SHANNON E., ROBERSON, ROBIN B., UHLMAN, ANDREW J., LEVI, NOAH J., MI, SARAH J., YUN JUN, JOO, BROADNEY, MIRANDA M., BRADY, SHEILA M., YANOVSKI, JACK A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699895/
https://ncbi.nlm.nih.gov/pubmed/30937899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12315
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