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Colchicine to decrease NLRP3-activated inflammation and improve obesity-related metabolic dysregulation
Obesity is a major risk-factor for the development of insulin resistance, type 2 diabetes, and cardiovascular disease. Circulating molecules associated with obesity, such as saturated fatty acids and cholesterol crystals, stimulate the innate immune system to incite a chronic inflammatory state. Stu...
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| Publicado no: | Med Hypotheses |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890167/ https://ncbi.nlm.nih.gov/pubmed/27241260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2016.04.039 |
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