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Antibodies to α5 chain of collagen IV are pathogenic in Goodpasture disease
Autoantibody against glomerular basement membrane (GBM) plays a direct role in the initiation and development of Goodpasture’s (GP) disease. The principal autoantigen is the non-collagenous domain 1 (NC1) of α3 chain of collagen IV, with two immunodominant epitopes, E(A)-α3 and E(B)-α3. We recently...
Guardat en:
| Publicat a: | J Autoimmun |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600521/ https://ncbi.nlm.nih.gov/pubmed/27117167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.04.001 |
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