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Locus-specific integration of extrachromosomal transgenes in C. elegans with the CRISPR/Cas9 system
We established a method to generate integration from extrachromosomal arrays with the CRISPR/Cas9 system. Multi-copy transgenes were integrated into the defined loci of chromosomes by this method, while a multi-copy transgene is integrated into random loci by previous methods, such as UV- and gamma-...
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| Pubblicato in: | Biochem Biophys Rep |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600330/ https://ncbi.nlm.nih.gov/pubmed/28955808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.11.017 |
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