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Bystander mechanism for complement-initiated early oligodendrocyte injury in neuromyelitis optica

Neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune inflammatory disease of the central nervous system in which immunoglobulin G antibodies against astrocyte water channel aquaporin-4 (AQP4-IgG) cause demyelination and neurological deficit. Injury to oligodendrocytes, which d...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Tradtrantip, Lukmanee, Yao, Xiaoming, Su, Tao, Smith, Alex J., Verkman, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600280/
https://ncbi.nlm.nih.gov/pubmed/28567523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1734-6
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