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Salmon: fast and bias-aware quantification of transcript expression using dual-phase inference

We introduce Salmon, a method for quantifying transcript abundance from RNA-seq reads that is accurate and fast. Salmon is the first transcriptome-wide quantifier to correct for fragment GC content bias, which we demonstrate substantially improves the accuracy of abundance estimates and the reliabil...

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Bibliografski detalji
Izdano u:Nat Methods
Glavni autori: Patro, Rob, Duggal, Geet, Love, Michael I, Irizarry, Rafael A, Kingsford, Carl
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600148/
https://ncbi.nlm.nih.gov/pubmed/28263959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4197
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