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Identification of Vaccinia Virus Replisome and Transcriptome Proteins by Isolation of Proteins on Nascent DNA Coupled with Mass Spectrometry

Poxviruses replicate within the cytoplasm and encode proteins for DNA and mRNA synthesis. To investigate poxvirus replication and transcription from a new perspective, we incorporated 5-ethynyl-2′-deoxyuridine (EdU) into nascent DNA in cells infected with vaccinia virus (VACV). The EdU-labeled DNA w...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Senkevich, Tatiana G., Katsafanas, George C., Weisberg, Andrea, Olano, Lisa R., Moss, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599757/
https://ncbi.nlm.nih.gov/pubmed/28747503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01015-17
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