Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants

Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. While bat, camel, and human DPP4 support MERS-CoV infection, several DPP4 orthologs, including mouse, ferret, hamster, and guinea pig DPP4, do not. Previous work revealed that glycosy...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Peck, Kayla M., Scobey, Trevor, Swanstrom, Jesica, Jensen, Kara L., Burch, Christina L., Baric, Ralph S., Heise, Mark T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599747/
https://ncbi.nlm.nih.gov/pubmed/28747502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00534-17
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