Glycosylation of Mouse DPP4 Plays a Role in Inhibiting Middle East Respiratory Syndrome Coronavirus Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. Mouse DPP4 (mDPP4) does not support MERS-CoV entry; however, changes at positions 288 and 330 can confer permissivity. Position 330 changes the charge and glycosylation state of mDPP4...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Peck, Kayla M., Cockrell, Adam S., Yount, Boyd L., Scobey, Trevor, Baric, Ralph S., Heise, Mark T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442375/
https://ncbi.nlm.nih.gov/pubmed/25653445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03445-14
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