Mouse Dipeptidyl Peptidase 4 Is Not a Functional Receptor for Middle East Respiratory Syndrome Coronavirus Infection

Human dipeptidyl peptidase 4 (hDPP4) was recently identified as the receptor for Middle East respiratory syndrome coronavirus (MERS-CoV) infection, suggesting that other mammalian DPP4 orthologs may also support infection. We demonstrate that mouse DPP4 cannot support MERS-CoV infection. However, em...

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Main Authors: Cockrell, Adam S., Peck, Kayla M., Yount, Boyd L., Agnihothram, Sudhakar S., Scobey, Trevor, Curnes, Nicole R., Baric, Ralph S., Heise, Mark T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Virus-Cell Interactions
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993820/
https://ncbi.nlm.nih.gov/pubmed/24574399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03764-13
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