NKp46 Recognizes the Sigma1 Protein of Reovirus: Implications for Reovirus-Based Cancer Therapy

The recent approval of oncolytic virus for therapy of melanoma patients has increased the need for precise evaluation of the mechanisms by which oncolytic viruses affect tumor growth. Here we show that the human NK cell-activating receptor NKp46 and the orthologous mouse protein NCR1 recognize the r...

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Udgivet i:J Virol
Main Authors: Bar-On, Yotam, Charpak-Amikam, Yoav, Glasner, Ariella, Isaacson, Batya, Duev-Cohen, Alexandra, Tsukerman, Pinchas, Varvak, Alexander, Mandelboim, Michal, Mandelboim, Ofer
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599737/
https://ncbi.nlm.nih.gov/pubmed/28724773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01045-17
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