NKp46 Recognizes the Sigma1 Protein of Reovirus: Implications for Reovirus-Based Cancer Therapy

The recent approval of oncolytic virus for therapy of melanoma patients has increased the need for precise evaluation of the mechanisms by which oncolytic viruses affect tumor growth. Here we show that the human NK cell-activating receptor NKp46 and the orthologous mouse protein NCR1 recognize the r...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bar-On, Yotam, Charpak-Amikam, Yoav, Glasner, Ariella, Isaacson, Batya, Duev-Cohen, Alexandra, Tsukerman, Pinchas, Varvak, Alexander, Mandelboim, Michal, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599737/
https://ncbi.nlm.nih.gov/pubmed/28724773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01045-17
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