Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression

Natural Killer (NK) cells employ activating receptors like the Natural Cytotoxicity Receptors (NCRs: NKp30, NKp44 and NKp46), of which only NKp46 has a mouse orthologue (Ncr1), to eliminate abnormal cells. NKp46/Ncr1 is considered a selective marker for NK cells, although it is also found on a subse...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Glasner, Ariella, Isaacson, Batya, Viukov, Sergey, Neuman, Tzahi, Friedman, Nehemya, Mandelboim, Michal, Sexl, Veronika, Hanna, Jacob H., Mandelboim, Ofer
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638832/
https://ncbi.nlm.nih.gov/pubmed/29026144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12998-w
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