Murine Gammaherpesvirus 68 Expressing Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) Reveals both Functional Conservation and Divergence in LANA Homologs

Latency-associated nuclear antigen (LANA) is a multifunctional protein encoded by members of the Rhadinovirus genus of gammaherpesviruses. Studies using murine gammaherpesvirus 68 (MHV68) demonstrated that LANA is important for acute replication, latency establishment, and reactivation in vivo. Desp...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Gupta, Arundhati, Oldenburg, Darby G., Salinas, Eduardo, White, Douglas W., Forrest, J. Craig
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599733/
https://ncbi.nlm.nih.gov/pubmed/28747501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00992-17
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