Murine Gammaherpesvirus 68 Expressing Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) Reveals both Functional Conservation and Divergence in LANA Homologs

Latency-associated nuclear antigen (LANA) is a multifunctional protein encoded by members of the Rhadinovirus genus of gammaherpesviruses. Studies using murine gammaherpesvirus 68 (MHV68) demonstrated that LANA is important for acute replication, latency establishment, and reactivation in vivo. Desp...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gupta, Arundhati, Oldenburg, Darby G., Salinas, Eduardo, White, Douglas W., Forrest, J. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599733/
https://ncbi.nlm.nih.gov/pubmed/28747501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00992-17
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