Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication

Tumor suppressor p53 is activated in response to numerous cellular stresses, including viral infection. However, whether murine gammaherpesvirus 68 (MHV68) provokes p53 during the lytic replication cycle has not been extensively evaluated. Here, we demonstrate that MHV68 lytic infection induces p53...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Sifford, Jeffrey M., Stahl, James A., Salinas, Eduardo, Forrest, J. Craig
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810692/
https://ncbi.nlm.nih.gov/pubmed/26676792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02867-15
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