Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication

Tumor suppressor p53 is activated in response to numerous cellular stresses, including viral infection. However, whether murine gammaherpesvirus 68 (MHV68) provokes p53 during the lytic replication cycle has not been extensively evaluated. Here, we demonstrate that MHV68 lytic infection induces p53...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Sifford, Jeffrey M., Stahl, James A., Salinas, Eduardo, Forrest, J. Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810692/
https://ncbi.nlm.nih.gov/pubmed/26676792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02867-15
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