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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment
The ETS transcription factor Etv2 is necessary and sufficient for the generation of hematopoietic and endothelial cells. However, upstream regulators of Etv2 in hemangiogenesis, generation of hematopoietic and endothelial cells, have not been clearly addressed. Here we track the developmental route...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599515/ https://ncbi.nlm.nih.gov/pubmed/28912455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00667-5 |
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