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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment

The ETS transcription factor Etv2 is necessary and sufficient for the generation of hematopoietic and endothelial cells. However, upstream regulators of Etv2 in hemangiogenesis, generation of hematopoietic and endothelial cells, have not been clearly addressed. Here we track the developmental route...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhao, Haiyong, Choi, Kyunghee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599515/
https://ncbi.nlm.nih.gov/pubmed/28912455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00667-5
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