Biochemical, physiologic, and clinical effects of L-methylfolate in schizophrenia: A randomized controlled trial

Folic acid supplementation confers modest benefit in schizophrenia, but its effectiveness is influenced by common genetic variants in the folate pathway that hinder conversion to its active form. We examined physiologic and clinical effects of L-methylfolate, the fully reduced and bioactive form of...

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Publicat a:Mol Psychiatry
Autors principals: Roffman, Joshua L, Petruzzi, Liana J., Tanner, Alexandra S., Brown, Hannah E., Eryilmaz, Hamdi, Ho, New Fei, Giegold, Madeline, Silverstein, Noah J., Bottiglieri, Teodoro, Manoach, Dara S., Smoller, Jordan W., Henderson, David C., Goff, Donald C.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599314/
https://ncbi.nlm.nih.gov/pubmed/28289280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.41
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