Biochemical, physiologic, and clinical effects of L-methylfolate in schizophrenia: A randomized controlled trial

Folic acid supplementation confers modest benefit in schizophrenia, but its effectiveness is influenced by common genetic variants in the folate pathway that hinder conversion to its active form. We examined physiologic and clinical effects of L-methylfolate, the fully reduced and bioactive form of...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Roffman, Joshua L, Petruzzi, Liana J., Tanner, Alexandra S., Brown, Hannah E., Eryilmaz, Hamdi, Ho, New Fei, Giegold, Madeline, Silverstein, Noah J., Bottiglieri, Teodoro, Manoach, Dara S., Smoller, Jordan W., Henderson, David C., Goff, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599314/
https://ncbi.nlm.nih.gov/pubmed/28289280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.41
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